18α-Glycyrrhetinic acid
18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis[1][2].
Product Specifications
CAS Number
1449-05-4
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; NF-κB; Proteasome
Type
Natural Products
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/18_alpha_-Glycyrrhetinic_acid.html
Concentration
10mM
Purity
99.87
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1(C)[C@@H](O)CC[C@@]2(C)[C@@]1([H])CC[C@]([C@@](CC[C@]3(C)[C@]4([H])C[C@@](C)(C(O)=O)CC3)(C)C4=C5)(C)[C@]2([H])C5=O
Molecular Formula
C30H46O4
Molecular Weight
470.68
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
NF-κB
Available Sizes
Frequently Asked Questions
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