ABBV-3373
ABBV-3373 is an anti-TNF antibody drug conjugate (ADC) . ABBV-3373 is composed of the humanized antibody Adalimumab (HY-P9908) conjugated with a glucocorticoid receptor modulator (HY-148436) . ABBV-3373 can be used in the study of rheumatoid arthritis[1].
Product Specifications
UNSPSC
12352203
Target
Antibody-Drug Conjugates (ADCs) ; Glucocorticoid Receptor; TNF Receptor
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Apoptosis; Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/abbv-3373.html
Purity
98.78
Smiles
[ABBV-3373]
References & Citations
[1]Qu P, et al. Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate. J Med Chem. 2022 Dec 8;65 (23) :15893-15934.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light
Scientific Category
ADC Related
Clinical Information
Phase 2
Available Sizes
Curated Selection
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