ABBV-3373

ABBV-3373 is an anti-TNF antibody drug conjugate (ADC) . ABBV-3373 is composed of the humanized antibody Adalimumab (HY-P9908) conjugated with a glucocorticoid receptor modulator (HY-148436) . ABBV-3373 can be used in the study of rheumatoid arthritis[1].

Product Specifications

UNSPSC

12352203

Target

Antibody-Drug Conjugates (ADCs) ; Glucocorticoid Receptor; TNF Receptor

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related; Apoptosis; Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/abbv-3373.html

Purity

98.78

Smiles

[ABBV-3373]

References & Citations

[1]Qu P, et al. Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate. J Med Chem. 2022 Dec 8;65 (23) :15893-15934.