MC-GGFG- (7ethanol-10NH2-11F-Camptothecin)
MC-GGFG- (7ethanol-10NH2-11F-Camptothecin) (compound 141) is a drug-linker conjugates for ADC. MC-GGFG- (7ethanol-10NH2-11F-Camptothecin) is a MC-GGFG- (7ethanol-10NH2-11F-Camptothecin) with protease cleavable MC-GGFG linker[1].
Product Specifications
CAS Number
[2987937-38-0]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-ggfg-7ethanol-10nh2-11f-camptothecin.html
Purity
95.61
Solubility
DMSO : 110 mg/mL (ultrasonic)
Smiles
OCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(F)=C(NC(CNC([C@@H](NC(CNC(CNC(CCCCCN6C(C=CC6=O)=O)=O)=O)=O)CC7=CC=CC=C7)=O)=O)C=C51
Molecular Formula
C46H47FN8O12
Molecular Weight
922.91
References & Citations
[1]Jeffrey A. Toretsky, et al. Camptothecin analogues, conjugates and methods of use. WO2022246576A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
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