Decapeptide-12
Decapeptide-12, a small oligopeptide, is a tyrosinase inhibitor that interacts with C-terminal residue of tyrosinase (Kd: 61.1 μM) . Decapeptide-12 is a competitive inhibitor of mushroom tyrosinase (IC50: 40 μM) . Decapeptide-12 also increases transcription of SIRT. Decapeptide-12 reduces melanin content in melanocytes. Decapeptide-12 is used for the research of melanogenesis, senescence, inflammation [1][2][3].
Product Specifications
CAS Number
137665-91-9
UNSPSC
12352209
Target
Sirtuin; Tyrosinase
Type
Peptides
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/decapeptide-12.html
Purity
99.95
Solubility
H2O : ≥ 100 mg/mL
Smiles
[Y][R]S[R]([Y]=S=S=[W][Y])[K]
Molecular Formula
C65H90N18O17
Molecular Weight
1395.52
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
RPS3AP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
Benchtop Shaking Incubator with Universal Platform (480144)
