SphK1&2-IN-1
SphK1&2-IN-1 is a SphK inhibitor targeting to SphK1 and SphK2. SphK1&2-IN-1 has thermal stability[1][2].
Product Specifications
CAS Number
1415662-57-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
SphK
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sphk1-2-in-1.html
Purity
99.33
Solubility
DMSO : 31.25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC1=C(C=CC(/C=C/C(NC2=NC=CS2)=O)=C1)OC
Molecular Formula
C14H14N2O3S
Molecular Weight
290.34
Precautions
H302, H315, H319
References & Citations
[1]Vogt D, et al. Design, synthesis and evaluation of 2-aminothiazole derivatives as sphingosine kinase inhibitors. Bioorg Med Chem. 2014 Oct 1;22 (19) :5354-67. |[2]Nong W, et al. Synthesis and biological evaluation of a new series of cinnamic acid amide derivatives as potent haemostatic agents containing a 2-aminothiazole substructure. Bioorg Med Chem Lett. 2017 Sep 15;27 (18) :4506-4511.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SphK1; SphK2
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040257-500 1x 500 µL
Cytokeratin, HMW (AE-3), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940177-100 1x 100 µL
CD50 (ICAM-3) (101-1D2), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400674-100 1x 100 µL
Cytokeratin 10 (LH2), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402222-100 1x 100 µL
Human Kappa Light Chain (B-Cell Marker) (rL1C1), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details