EBOV/MARV-IN-1
EBOV/MARV-IN-1 is a potent inhibitor of Ebola virus (EBOV) and Marburg virus (MARV), with broad-spectrum activity (EC50=0.31, and 0.82 μM, respectively) and low cytotoxicity (SI>100) in HeLa cells[1].
Product Specifications
CAS Number
[2479465-67-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Filovirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ebov-marv-in-1.html
Purity
99.14
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(N2CCC(C)CC2)C(C(F)(F)F)=C1)C3=CC=C(CN4CCOCC4)C=C3
Molecular Formula
C25H30F3N3O2
Molecular Weight
461.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Gaisina IN, et, al. Discovery and Structural Optimization of 4- (Aminomethyl) benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections. J Med Chem. 2020 Jul 9;63 (13) :7211-7225.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EBOV; MARV
Available Sizes
Curated Selection
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