N-Bromoacetamide

N-Bromoacetamide can irreversibly remove sodium channel inactivation in the cytoplasmic face of the membrane, also decreasing K current rapid inactivation[1][2].

Product Specifications

CAS Number

[79-15-2]

UNSPSC

12352211

Hazard Statement

H314, H319, H335

Target

Potassium Channel; Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n-bromoacetamide.html

Purity

99.95

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

CC(NBr)=O

Molecular Formula

C2H4BrNO

Molecular Weight

137.96

Precautions

H314, H319, H335

References & Citations

[1]Matteson DR, et al. Modification of K channel inactivation by papain and N-bromoacetamide. Biophys J. 1988;53 (4) :641-645.|[2]Patlak J, et al. Effect of N-bromoacetamide on single sodium channel currents in excised membrane patches. J Gen Physiol. 1982;79 (3) :333-351.