CHN1, Human (sf9, His-GST)

CHN1 protein, a GTPase-activating protein for p21-rac, acts as a phorbol ester receptor and is crucial in assembling neuronal locomotor circuits. It serves as a direct effector of EPHA4, linking EPHA4 activation to RAC1 regulation. CHN1's interaction with EPHA4 influences axon guidance signaling pathways, impacting the development and organization of essential neuronal circuits for proper locomotion. CHN1 Protein, Human (sf9, His-GST) is the recombinant human-derived CHN1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.