EphA2 agonist 1
EphA2 agonist 1 (Compound 7bg) is a potent EphA2 receptor agonist. EphA2 agonist 1 shows great potency and selectivity toward EphA2 overexpressed glioblastoma cells and stimulates EphA2 phosphorylation[1].
Product Specifications
CAS Number
2611459-57-3
UNSPSC
12352005
Target
Ephrin Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/epha2-agonist-1.html
Purity
99.32
Solubility
DMSO : ≥ 50 mg/mL
Smiles
COC1=C(C=C2C(N=C(N=C2N)N3CCN(CC3)C(C4=CC(NC(OCCOCCOCCOC(NC5=CC=CC(C(N6CCN(CC6)C7=NC8=CC(OC)=C(C=C8C(N)=N7)OC)=O)=C5)=O)=O)=CC=C4)=O)=C1)OC
Molecular Formula
C50H58N12O12
Molecular Weight
1019.07
References & Citations
[1]Orahoske CM, et al. Dimeric small molecule agonists of EphA2 receptor inhibit glioblastoma cell growth. Bioorg Med Chem. 2020 Sep 15;28 (18) :115656.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC942600-100 1x 100 µL
EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
PKSV030254 100 µg
Recombinant SIV (isolate 216.94.A2) gp120 Protein (His Tag)
Sign In for Pricing
View Details 
