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Mouse ICAM-3 Antibody

Mouse monoclonal to ICAM-3. Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a type I transmembrane glycoprotein, which normally contain 2-9 immunoglobulin-like C2-type domains, and binds to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM-3 has previously been implicated in apoptotic cell clearance, although its precise role in the clearance process is ill defined.

Product Specifications

UniProt

P32942

Reactivity

Human

Clonality

Monoclonal

Clone

JA4

Conjugation

Unconjugated

Source

JA4 is a mouse monoclonal IgG1/k antibody derived by fusion of mouse Ag8.653 cells with spleen cells from a BALB/c mouse immunized with an ICAM-3/HEK transfectant.

Field of Research

Neuroscience

Form

Each vial contains 100 μl 1 mg/ml purified monoclonal antibody in PBS containing 0.09% sodium azide.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

ELISA, FC, ICC, IHC-Fr, IP, WB

Host or Source

Mouse

Isotype

IgG1/k

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