(-) -Cedrene

(-) -Cedrene (α-cedrene) is a major constituent that can be found in essential oils. (-) -Cedrene (α-cedrene) is a natural, orally active ligand of mouse olfactory receptor 23, which induces skeletal muscle hypertrophy in mice. (-) -Cedrene exhibits trypanocidal (Trypanosoma b. brucei) (IC50 = 4.07 μg/mL) . (-) -Cedrene is antileukemic in vitro (IC50 = 22.2 μg/mL) . (-) -Cedrene has antimicrobial activity against anaerobic bacteria and yeast. (-) -Cedrene exhibits anti-obesity activity[1][2].

Product Specifications

CAS Number

[469-61-4]

Product Name Alternative

α-cedrene

UNSPSC

12352211

Hazard Statement

H315, H319, H400

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/minus-cedrene.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@H]1[C@]2(C[C@H]3C(C)=CC2)[C@](CC1)([H])C3(C)C

Molecular Formula

C15H24

Molecular Weight

204.35

Precautions

H315, H319, H400

References & Citations

[1]Tae Hwan Kim, et al. In Vivo Absorption and Disposition of α-Cedrene, a Sesquiterpene Constituent of Cedarwood Oil, in Female and Male Rats. Drug Metab Pharmacokinet. 2015 Apr;30 (2) :168-73.|[2]Tong, T., et al., (2018) . α-Cedrene, a Newly Identified Ligand of MOR23, Increases Skeletal Muscle Mass and Strength. Molecular nutrition & food research, 62 (15), e1800173.