Aspartame-d3

Aspartame-d3 is the deuterium labeled Aspartame. Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener. Aspartame is composed of phenylalanine (50%), aspartic acid (40%) and methanol (10%) [1][2].

Product Specifications

CAS Number

[1356841-28-5]

Product Name Alternative

SC-18862-d3

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Neurological Disease

Solubility

10 mM in DMSO

Smiles

OC(C[C@H](N)C(N[C@H](C(OC([2H])([2H])[2H])=O)CC1=CC=CC=C1)=O)=O

Molecular Formula

C14H15D3N2O5

Molecular Weight

297.32

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Magnuson, B.A., et al., Aspartame: a safety evaluation based on current use levels, regulations, and toxicological and epidemiological studies. Crit Rev Toxicol, 2007. 37 (8) : p. 629-727.|[3]Humphries, P., E. Pretorius, and H. Naude, Direct and indirect cellular effects of aspartame on the brain. Eur J Clin Nutr, 2008. 62 (4) : p. 451-62.