NSC 405020
NSC 405020 is a specific MMP14 inhibitor. NSC 405020 can directly interact with the hemopexin domain of MMP14. NSC 405020 reduces the expression of full length and active cleaved Notch3 (NICD3) . NSC 405020 can be used to research vestibular schwannoma, hemostasis and thrombosis[1][2][3].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/NSC-405020.html
Purity
99.63
Solubility
DMSO : ≥ 260 mg/mL
Smiles
O=C(NC(C)CCC)C1=CC=C(Cl)C(Cl)=C1
Molecular Formula
C12H15Cl2NO
Molecular Weight
260.16
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15827/NSC-405020-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15827/NSC-405020-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[7497-07-6]
Available Sizes
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