Agatolimod (sodium)

Agatolimod sodium (ODN 2006) is a class B CpG ODN and is a TLR9 agonist. Agatolimod sodium can be used as vaccine adjuvant. Agatolimod sodium can be used for the research of cancer. Sequence: 5’-TCGTCGTTTTGTCGTTTTGTCGTT-3’[1][2].

Product Specifications

CAS Number

[541547-35-7]

Product Name Alternative

ODN 2006 sodium; ODN 7909 sodium; PF-3512676 sodium; CpG 7909 sodium

UNSPSC

12352208

Target

Toll-like Receptor (TLR)

Type

Oligonucleotides

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/agatolimod-sodium.html

Purity

99.13

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

[Agatolimod(sodium)]

Molecular Formula

C236H303N70O133P23S23Na23

Molecular Weight

7699 (free acid)

References & Citations

[1]Yan L, et al. CpG-ODN 7909 increases radiation sensitivity of radiation-resistant human lung adenocarcinoma cell line by overexpression of Toll-like receptor 9. Cancer Biother Radiopharm. 2013 Sep;28 (7) :559-64.|[2]Cooper CL, et al. Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine. Vaccine. 2004 Aug 13;22 (23-24) :3136-43.