Apoptosis inducer 32
Product Specifications
UNSPSC Description
Apoptosis inducer 32 (Compound 7g) is an apoptosis inducer with a KD of 42 μM, showing anti-tumor activity. Apoptosis inducer 32 caused significant cellular morphological changes in MDA-MB-231 cells, including membrane bubbling, nuclear fragmentation, and apoptotic body formation. The IC50 of Apoptosis inducer 32 in MCF-7, MDA-MB-231, and HEK cells is 4.77, 6.56 and 337.8 μM respectively[1].
Target Antigen
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apoptosis-inducer-32.html
Smiles
O=C(NC1=CC=C(Cl)C=C1Cl)NC2=C3C([C@@]([C@@]4([H])OC(C5=C4C=CC(OC)=C5OC)=O)([H])N(C)CC3)=C(OC)C6=C2OCO6
Molecular Weight
616.45
References & Citations
[1]Pratyush Pragyandipta, et al. In silico inspired design of urea noscapine congeners as anticancer agents: Chemical synthesis and experimental evaluation using breast cancer cells and a xenograft mouse model. Eur J Med Chem. 2025 Jan 15:282:117091.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168720/Apoptosis-inducer-32-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168720/
Clinical Information
No Development Reported
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