Engeletin
Product Specifications
UNSPSC Description
Engeletin is a flavanonol glycoside isolated from Smilax glabra Roxb. , inhibits NF-κB signaling-pathway activation, and possesses anti-inflammatory, analgesic, diuresis, detumescence, and antibiosis effects.
Target Antigen
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Engeletin.html
Purity
99.88
Solubility
DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
OC1=CC(O)=C(C([C@H](O[C@@]2([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O2)[C@@H](C3=CC=C(O)C=C3)O4)=O)C4=C1
Molecular Weight
434.39
References & Citations
[1]Wu H, et al. Engeletin Alleviates Lipopolysaccharide-Induced Endometritis in Mice by Inhibiting TLR4-mediated NF-κB Activation. J Agric Food Chem. 2016 Aug 10;64(31):6171-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0436/Engeletin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0436/Engeletin-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
572-31-6
Available Sizes
Curated Selection
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