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TC-Mps1-12

Product Specifications

UNSPSC Description

TC-Mps1-12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor, with an IC50 of 6.4 nM[1].

Target Antigen

Mps1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Cytoskeleton

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tc-mps1-12.html

Purity

99.76

Solubility

10 mM in DMSO

Smiles

N#CC1=C(N=C(NC2=CC=C(C(N)=O)C=C2)C=C1N)NC(C)(C)C

Molecular Weight

324.38

References & Citations

[1]Kusakabe K, et al. Diaminopyridine-based potent and selective mps1 kinase inhibitors binding to an unusual flipped-Peptide conformation. ACS Med Chem Lett. 2012 Jun 6;3(7):560-4.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-110115/TC-Mps1-12-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-110115/TC-Mps1-12-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1206170-62-8

Available Sizes

Curated Selection

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