TC-Mps1-12
TC-Mps1-12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor, with an IC50 of 6.4 nM[1].
Product Specifications
CAS Number
[1206170-62-8]
UNSPSC
12352005
Target
Mps1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tc-mps1-12.html
Purity
99.76
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
N#CC1=C(N=C(NC2=CC=C(C(N)=O)C=C2)C=C1N)NC(C)(C)C
Molecular Formula
C17H20N6O
Molecular Weight
324.38
References & Citations
[1]Kusakabe K, et al. Diaminopyridine-based potent and selective mps1 kinase inhibitors binding to an unusual flipped-Peptide conformation. ACS Med Chem Lett. 2012 Jun 6;3 (7) :560-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6397046-01 0.1 mL
TRAF4 (TNF Receptor Associated Factor 4, TNF Receptor-associated Factor 4, TRAF 4, TRAF-4, Cysteine-rich Domain Associated with RING and Traf Domains Protein 1, CART1, Metastatic Lymph Node Gene 62 Protein, MLN 62, MLN62, RING Finger Protein 83, RNF83) (M
Ask
View Details 
MBS6397046-02 5x 0.1 mL
TRAF4 (TNF Receptor Associated Factor 4, TNF Receptor-associated Factor 4, TRAF 4, TRAF-4, Cysteine-rich Domain Associated with RING and Traf Domains Protein 1, CART1, Metastatic Lymph Node Gene 62 Protein, MLN 62, MLN62, RING Finger Protein 83, RNF83) (M
Ask
View Details YVV20701 100 μg
Recombinant Coxsackievirus A10/CA10 VP1/Capsid protein VP1 Protein, N-His
Ask
View Details