Syrosingopine
Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, which can reduce glycolysis and induce synthetic lethality in cancer cells when combine with metformin. Syrosingopine shows anti-hypertensive activity by depleting peripheral stores of norepinephrine[1][2].
Product Specifications
CAS Number
84-36-6
Product Name Alternative
Su 3118
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Monocarboxylate Transporter
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/syrosingopine.html
Concentration
10mM
Purity
99.52
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
[H][C@@]12C(NC3=C4C=CC(OC)=C3)=C4CCN1C[C@]5(C[C@@H](OC(C6=CC(OC)=C(OC(OCC)=O)C(OC)=C6)=O)[C@H](OC)[C@@H](C(OC)=O)[C@]5(C2)[H])[H]
Molecular Formula
C35H42N2O11
Molecular Weight
666.71
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MCT1; MCT4
Available Sizes
Frequently Asked Questions
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