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Butamirate (citrate)

Butamirate citrate is an orally active antitussive agent that acts centrally through the receptors in the brainstem. Butamirate citrate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect. Butamirate citrate inhibits glioblastoma (GBM) growth and STAT3 activity. Butamirate citrate can be used for the study of glioblastoma[1][2].

Product Specifications

CAS Number

[18109-81-4]

Product Name Alternative

CS-505

UNSPSC

12352005

Target

STAT

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/butamirate-citrate.html

Purity

99.88

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(OCCOCCN(CC)CC)C(CC)C1=CC=CC=C1.O=C(CC(C(O)=O)(O)CC(O)=O)O

Molecular Formula

C24H37NO10

Molecular Weight

499.55

References & Citations

[1]Płusa T. [Butamirate citrate in control of cough in respiratory tract inflammation]. Pol Merkur Lekarski. 2017 Aug 21;43 (254) :69-74. Polish.|[2]Lee SJ, et al. Application of the antitussive agents oxelaidin and butamirate as anti-glioma agents. Sci Rep. 2021 May 12;11 (1) :10145.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Curated Selection

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