Phenylpyropene A
Phenylpyropene A, a fungal metabolite, is a potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with an IC50 of 0.8 μM[1].
Product Specifications
CAS Number
189564-20-3
UNSPSC
12352005
Target
Acyltransferase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/phenylpyropene-a.html
Solubility
10 mM in DMSO
Smiles
O=C1OC(C2=CC=CC=C2)=CC3=C1[C@H](O)[C@@]4([H])[C@]([C@@H](OC(C)=O)C[C@@]5([H])[C@](C)(COC(C)=O)[C@@H](OC(C)=O)CC[C@@]54C)(C)O3
Molecular Formula
C32H38O10
Molecular Weight
582.64
References & Citations
[1]R Obata, et al. Chemical modification and structure-activity relationships of pyripyropenes. 3. Synthetic conversion of pyridine-pyrone moiety. J Antibiot (Tokyo) . 1997 Mar;50 (3) :229-36.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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