Pinosylvin

Pinosylvin is a pre-infectious stilbenoid toxin isolated from the heartwood of Pinus species, has anti-bacterial activities[1]. Pinosylvin is a resveratrol analogue, can induce cell apoptosis and autophapy in leukemia cells[2].

Product Specifications

CAS Number

[22139-77-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Autophagy; Bacterial

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/pinosylvin.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC(/C=C/C2=CC=CC=C2)=CC(O)=C1

Molecular Formula

C14H12O2

Molecular Weight

212.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Lee SK, et al. Antibacterial and antifungal activity of pinosylvin, a constituent of pine.Fitoterapia. 2005 Mar;76 (2) :258-60.|[2]Roupe KA, et al. Pharmacokinetics of selected stilbenes: rhapontigenin, piceatannol and pinosylvin in rats.J Pharm Pharmacol. 2006 Nov;58 (11) :1443-50.|[3]Song J, et al. Pinosylvin enhances leukemia cell death via down-regulation of AMPKα expression. Phytother Res. 2018 Oct;32 (10) :2097-2104.