NMDAR antagonist 1
NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective NMDAR antagonist[1].
Product Specifications
CAS Number
[2220162-06-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nmdar-antagonist-1.html
Purity
99.02
Solubility
DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NCCC1=CC=C(O)C=C1)[C@@H]2CCC3=NC4=CC=C(Br)C=C4CN32
Molecular Formula
C20H20BrN3O2
Molecular Weight
414.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang L, et al. Design, synthesis and bioevaluation of 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline-1-carboxylic acid derivatives as potent neuroprotective agents. Eur J Med Chem. 2018 May 10;151:27-38.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
