3-HTC
3-HTC is a chemical fluorescent probe. 3-HTC reacts reversibly with thiols and disulfides, and can be used to measure dynamic GSH/GSSH ratios in vitro as well as to monitor the reversible redox status of whole cell lysates (λmax: 448 nm in its reduced thiolate form, and a λmax 370-410 nm for the oxidized mixed disulfide) [1].
Product Specifications
CAS Number
1356543-39-9
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-htc.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C2=NC3=CC=CC=C3S2)=CC4=CC=C(S)C=C4O1
Molecular Formula
C16H9NO2S2
Molecular Weight
311.38
References & Citations
[1]Reddie KG, et al. Fluorescent coumarin thiols measure biological redox couples. Org Lett. 2012 Feb 3;14 (3) :680-3.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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