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3-HTC

3-HTC is a chemical fluorescent probe. 3-HTC reacts reversibly with thiols and disulfides, and can be used to measure dynamic GSH/GSSH ratios in vitro as well as to monitor the reversible redox status of whole cell lysates (λmax: 448 nm in its reduced thiolate form, and a λmax 370-410 nm for the oxidized mixed disulfide) [1].

Product Specifications

CAS Number

1356543-39-9

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3-htc.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C2=NC3=CC=CC=C3S2)=CC4=CC=C(S)C=C4O1

Molecular Formula

C16H9NO2S2

Molecular Weight

311.38

References & Citations

[1]Reddie KG, et al. Fluorescent coumarin thiols measure biological redox couples. Org Lett. 2012 Feb 3;14 (3) :680-3.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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