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(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH

Product Specifications

Product Name Alternative

VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH

UNSPSC Description

(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH (VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH) is a E3 ligase ligand-linker conjugate that contains on one end a VHL ligand. (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH is used in PROTAC technology[1].

Target Antigen

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-r-s-ahpc-boc-trans-3-aminocyclobutanol-pip-ch2cooh.html

Purity

99.31

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CN1CCC(O[C@H]2C[C@H](NC(OC(C)(C)C)=O)C2)CC1)N[C@H](C(N([C@H](C(N[C@@H](C)C3=CC=C(C=C3)C4=C(C)N=CS4)=O)C5)C[C@@H]5O)=O)C(C)(C)C

Molecular Weight

754.98

References & Citations

[1]Yimin Qian, et al. Compounds and methods for the targeted degradation of bromodomain-containing proteins. WO2017030814A1.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-991.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-131168/S-R-S-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-131168/S-R-S-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2086301-47-3

Available Sizes

Curated Selection

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