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ERAP1-IN-2

ERAP1-IN-2 (compound 3f) is an inhibitor of ERAP1 (endoplasmic reticulum aminopeptidase 1) . ERAP1-IN-2 has an IC50 value of 1.72 μM against hERAP1[1].

Product Specifications

UNSPSC

12352005

Target

Aminopeptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/erap1-in-2.html

Smiles

O=C(O)C1=CC=C(CC(SC(N2)=S)C2=O)C=C1

Molecular Formula

C11H9NO3S2

Molecular Weight

267.32

References & Citations

[1]Fougiaxis V, et al. First fragment-based screening identifies new chemotypes inhibiting ERAP1-metalloprotease. Eur J Med Chem. 2024 Sep 30;280:116926.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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