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Quazomotide

Quazomotide is a WT1 class II peptide epitope with sequences of RSDELVRHHNMHQRNMTKL. Quazomotide stimulates a peptide-specific CD4 (+) response, to recognize WT1 (+) tumor cells. Quazomotide is an immunological agent for active immunization, as well as an antineoplastic agent[1][2].

Product Specifications

CAS Number

935395-33-8

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/quazomotide.html

Solubility

10 mM in DMSO

Smiles

N=C(N)NCCC[C@H](N)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CCSC)C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@@H](CCSC)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)CC2=CN=CN2)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C98H164N38O29S2

Molecular Weight

2402.72

References & Citations

[1]May RJ, et al. Peptide epitopes from the Wilms' tumor 1 oncoprotein stimulate CD4+ and CD8+ T cells that recognize and kill human malignant mesothelioma tumor cells. Clin Cancer Res. 2007 Aug 1;13 (15 Pt 1) :4547-55.|[2]WHO Drug Information-World Health Organization (WHO) .

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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