Human Recombinant FcγRIIb/CD32B

<strong>Human Recombinant FcγRIIb/CD32B </strong>_x000D_ <strong>Catalog number:</strong> B2017031_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 20.8 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> CDw32, Fc-γ RII-b, FcγRIIB, FcRII-b, IgG Fc Receptor II-b, Low Affinity Immunoglobulin Gamma Fc Region Receptor II-b_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Veri MC, Gorlatov S, Li H, Burke S, Johnson S, Stavenhagen J, Stein KE, Bonvini E, Koenig S. Monoclonal antibodies capable of discriminating the human inhibitory Fcgamma-receptor IIB (CD32B) from the activating Fcgamma-receptor IIA (CD32A): biochemical, biological and functional characterization Immunology. 2007 Jul;121(3):392-404._x000D_ 2: Crawford JR, Pilling D, Gomer RH. FcγRI mediates serum amyloid P inhibition of fibrocyte differentiation J Leukoc Biol. 2012 Oct;92(4):699-711._x000D_ 3: Moraru M, Perez-Portilla A, Al-Akioui Sanz K, Blazquez-Moreno A, Arnaiz-Villena A, Reyburn HT, Vilches C. FCGR Genetic Variation in Two Populations From Ecuador Highlands-Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene Front Immunol. 2021 May 24;12:615645._x000D_ 4: Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F. C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes J Leukoc Biol. 2008 Oct;84(4):1109-19._x000D_ 5: Hör S, Ziv T, Admon A, Lehner PJ. Stable isotope labeling by amino acids in cell culture and differential plasma membrane proteome quantitation identify new substrates for the MARCH9 transmembrane E3 ligase Mol Cell Proteomics. 2009 Aug;8(8):1959-71._x000D_ 6: Xu Z, Liu L, Cui Z, Bi K, Zhang N, Zhang Y, Liu Z. The Unique Inhibitory IgG Receptor--FcγRIIb Protein Pept Lett. 2018;25(11):966-972._x000D_ 7: Zhang K, Zhu D, Kepley C, Terada T, Saxon A. Chimeric human fcgamma-allergen fusion proteins in the prevention of allergy Immunol Allergy Clin North Am. 2007 Feb;27(1):93-103._x000D_ 8: Saxon A, Kepley C, Zhang K. "Accentuate the negative, eliminate the positive": engineering allergy therapeutics to block allergic reactivity through negative signaling J Allergy Clin Immunol. 2008 Feb;121(2):320-5._x000D_ 9: Magnusson SE, Andrén M, Nilsson KE, Sondermann P, Jacob U, Kleinau S. Amelioration of collagen-induced arthritis by human recombinant soluble FcgammaRIIb Clin Immunol. 2008 May;127(2):225-33._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/35410313">10: Jiang VC, Liu Y, Jordan A, Leeming A, McIntosh J, Huang S, Zhang R, Cai Q, Chen Z, Li Y, Che Y, Nie L, Karlsson I, Mårtensson L, Kovacek M, Teige I, Frendéus B, Wang M. Targeting FcγRIIB by antagonistic antibody BI-1206 improves the efficacy of rituximab-based therapies in aggressive mantle cell lymphoma J Hematol Oncol. 2022 Apr 11;15(1):42. </a>_x000D_ _x000D_ <strong>Products Related to Human Recombinant FcγRIIb/CD32B can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>