Purified Anti-Human CD80 Antibody[2F4]

B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20‑100 fold higher affinity than CD28 and is involved in the down‑regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages.

LAB; CTLA-4 counter-receptor B; T-lymphocyte activation antigen CD; B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7; CD80; CD28LGB7-1 antigen; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; CTLA-4 counter-receptor B7.1; B7-1; BB1; B lymphocyte activation antigen B7; B7-1 antigen; B7-1 antigen) ; CD28 antigen ligand 1; CD80 antigen; CD80 antigen (CD28 antigen ligand 1; CD80 molecule; Costimulatory factor CD80; costimulatory molecule variant IgV-CD80