(S) -S007-1558
(S) -S007-1558 (compound 5) is a glycoprotein VI (GPVI) platelet receptor antagonist. (S) -S007-1558 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM[1].
Product Specifications
CAS Number
[1327156-14-8]
Product Name Alternative
GPVI antagonist 1
UNSPSC
12352005
Target
Glycoprotein VI
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gpvi-antagonist-1.html
Purity
99.78
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C([C@@H]1CC2=C(CN1S(=O)(C3=CC=C(OC)C=C3)=O)NC4=C2C=CC=C4)N
Molecular Formula
C19H19N3O4S
Molecular Weight
385.44
References & Citations
[1]Holly Foster, et al. A Comparative Assessment Study of Known Small-molecule GPVI Modulators. ACS Med Chem Lett. 2022 Jan 20;13 (2) :171-181.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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