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(S) -S007-1558

(S) -S007-1558 (compound 5) is a glycoprotein VI (GPVI) platelet receptor antagonist. (S) -S007-1558 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM[1].

Product Specifications

CAS Number

[1327156-14-8]

Product Name Alternative

GPVI antagonist 1

UNSPSC

12352005

Target

Glycoprotein VI

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/gpvi-antagonist-1.html

Purity

99.78

Solubility

DMSO : ≥ 50 mg/mL

Smiles

O=C([C@@H]1CC2=C(CN1S(=O)(C3=CC=C(OC)C=C3)=O)NC4=C2C=CC=C4)N

Molecular Formula

C19H19N3O4S

Molecular Weight

385.44

References & Citations

[1]Holly Foster, et al. A Comparative Assessment Study of Known Small-molecule GPVI Modulators. ACS Med Chem Lett. 2022 Jan 20;13 (2) :171-181.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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