Lactic acid-d3 (sodium) (60% w/w in water)

Lactic acid-d3 (DL-Lactic acid-d3) sodium (60% in water) is the deuterium labeled Lactic acid sodium (60% in water) (HY-B2227B) . Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity[1][2]. Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative[3].

Product Specifications

CAS Number

[1219802-24-0]

Product Name Alternative

DL-Lactic acid-d3 (sodium) ; E-270-d3 (sodium)

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Bacterial; Endogenous Metabolite; Hydroxycarboxylic Acid Receptor (HCAR) ; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease; Others

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology

Purity

98.00

Solubility

10 mM in DMSO|DMSO : ≥ 100mg/mL

Smiles

O=C(O[Na])C(O)C([2H])([2H])[2H]

Molecular Formula

C3H2D3NaO3

Molecular Weight

115.08

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Lucia Longhitano, et al. Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence Phenotype. Int J Mol Sci. 2022 Dec 20;24 (1) :24.|[2]Qiang Feng, et al. Lactate increases stemness of CD8 + T cells to augment anti-tumor immunity. Nat Commun. 2022 Sep 6;13 (1) :4981. |[3]Sallam KI. Antimicrobial and antioxidant effects of sodium acetate, sodium lactate, and sodium citrate in refrigerated sliced salmon. Food Control. 2007 May;18 (5) :566-575.