BMPO

BMPO (BocMPO) is a cell-permeable superior spin trap with favorable chemical and spectroscopic features. BMPO (BocMPO) can be used for detecting thiyl radicals, hydroxyl radicals, superoxide anions and glutathiyl radicals[1].

Product Specifications

CAS Number

[387334-31-8]

Product Name Alternative

BocMPO

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/bmpo.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1(C)[N+]([O-])=CCC1)OC(C)(C)C

Molecular Formula

C10H17NO3

Molecular Weight

199.25

Precautions

H315, H319

References & Citations

[1]H Zhao, et al. Synthesis and biochemical applications of a solid cyclic nitrone spin trap: a relatively superior trap for detecting superoxide anions and glutathiyl radicals. Free Radic Biol Med|[2]Hongtao Zhao, et al. Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence. Proc Natl Acad Sci U S A|[3]Nadeem Khan, et al. Spin traps: in vitro toxicity and stability of radical adducts. Free Radic Biol Med. 2003 Jun 1;34 (11) :1473-81.