Tubulin inhibitor 44
Selected Variant
HY-161614
Size: 1 Each
Tubulin inhibitor 44 (Compound 26r) is an inhibitor for tubullin. Tubulin inhibitor 44 exhibits cytotoxicity in cancer cells NCI-H460, BxPC-3 and HT-29, with IC50s of 0.96, 0.66 and 0.61 nM, respectively[1].
Product Specifications
CAS Number
3025180-36-0
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-inhibitor-44.html
Solubility
10 mM in DMSO
Smiles
O=C(N/C(C(N/1)=O)=C\C2=CC=C(C=N2)OCCCC)C1=C\C3=CC(C(C4=CC=C(C=C4)F)=O)=CC=C3
Molecular Formula
C28H24FN3O4
Molecular Weight
485.51
References & Citations
[1]Wang S, et al., Design, synthesis, and structure-activity relationship study of novel plinabulin derivatives as anti-tumor agents based on the co-crystal structure. Mol Divers. 2024 Apr 23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC471190-500 1x 500 µL
Cytokeratin 18 (KRT18/1190), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682651-500 1x 500 µL
Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682756-100 1x 100 µL
MCM7 (Proliferation Marker) (MCM7/2756R), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNUB2098-100 1x 100 µL
Catenin, beta (CTNNB1) (CTNNB1/2098), 0.2mg/mL
Sign In for Pricing
View Details 
BNUM2587-50 1x 50 µL
Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), 1mg/mL
Sign In for Pricing
View Details