8-NBD-cAMP (sodium)
Product Specifications
UNSPSC Description
8-NBD-cAMP sodium is a fluorescently labeled cyclic adenosine phosphate (cAMP) analogue. 8-NBD-cAMP sodium retains a similar biological activity to cAMP, regulating their activity by binding to specific proteins such as EPACs or PKA. 8-NBD-cAMP sodium can be used in fluorescent competitive binding experiments to evaluate the binding affinity of newly synthesized EPAC1 agonists to EPAC1 proteins[1].
Target Antigen
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/8-nbd-camp-sodium.html
Smiles
NC1=C(N=C2SCCNC3=CC=C([N+]([O-])=O)C4=NON=C43)C(N2[C@@]5([H])[C@H](O)[C@@](OP(OC6)(O[Na])=O)([H])[C@]6([H])O5)=NC=N1
Molecular Weight
589.41
References & Citations
[1]Wang P, et al. Synthesis and biochemical evaluation of noncyclic nucleotide exchange proteins directly activated by cAMP 1 (EPAC1) regulators[J]. Journal of medicinal chemistry, 2020, 63(10): 5159-5184.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-134308/8-NBD-cAMP-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-134308/
Clinical Information
No Development Reported
CAS Number
221905-51-7
Curated Selection
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