ONO-0740556

ONO-0740556 is a potent Gi-coupled human lysophosphatidic acid receptor 1 (LPA1) agonist with an EC50 value of 0.26 nM[1].

Product Specifications

CAS Number

[2250210-69-4]

UNSPSC

12352005

Target

LPL Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ono-0740556.html

Purity

99.78

Solubility

DMSO : 75 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=P(O)(O)OC[C@@H](CO)NC(CCCCC1=C(C=CC=C1)CCCCCC)=O

Molecular Formula

C20H34NO6P

Molecular Weight

415.46

References & Citations

[1]Hiroaki Akasaka, et al. Structure of the active Gi-coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun. 2022 Sep 15;13 (1) :5417.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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