Brostallicin
Brostallicin (PNU-166196) is a DNA alkylating agent with potent cytotoxicity and low myelotoxicity[1].
Product Specifications
CAS Number
203258-38-2
Product Name Alternative
PNU-166196
UNSPSC
12352005
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brostallicin.html
Smiles
O=C(C(Br)=C)NC1=CN(C)C(C(NC2=CN(C)C(C(NC3=CN(C)C(C(NC4=CN(C)C(C(NCCNC(N)=N)=O)=C4)=O)=C3)=O)=C2)=O)=C1.Cl
Molecular Formula
C30H36BrClN12O5
Molecular Weight
760.04
References & Citations
[1]Brostallicin (PNU-166196), a new minor groove DNA binder: preclinical and clinical activity
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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