KRAS G12C inhibitor 15

2349393-21-9

12352005

Ras

Reference compound

GPCR/G Protein; MAPK/ERK Pathway

Cancer-Kinase/protease

Cancer

https://www.medchemexpress.com/kras-g12c-inhibitor-15.html

98.47

DMSO : 193.33 mg/mL (ultrasonic)

FC1=C(N=CC(N2C)=C3N4[C@H](CN(C(C=C)=O)[C@H](C)C4)C2=O)C3=CC(Cl)=[C@@]1[C@@]5=C(F)C=CC=C5O

C25H21ClF2N4O3

498.91

[1]Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.

Blue Ice

-20°C (Powder, protect from light, stored under nitrogen)

Reference compound1

No Development Reported

K-Ras