Adhesamine (diTFA)
Adhesamine diTFA is a dumbbell-shaped molecule that activates the MAPK/FAK pathway. Adhesamine promotes the adhesion and growth of mammalian cells, accelerates the differentiation of primary cultured mouse hippocampal neurons, and enhances their survival rate[1].
Product Specifications
CAS Number
1201698-09-0
UNSPSC
12352005
Target
FAK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/adhesamine-ditfa.html
Purity
95.74
Solubility
DMSO : 2.2 mg/mL (ultrasonic)
Smiles
O=CC1=C(N2CC[N+]3(CC[N+]4(CC3)CCN(CC4)C5=C(C=O)C(Cl)=NC(SC)=N5)CC2)N=C(SC)N=C1Cl.O=C(C(F)(F)F)[O-].O=C(C(F)(F)F)[O-]
Molecular Formula
C28H32Cl2F6N8O6S2
Molecular Weight
825.63
References & Citations
[1]Hoshino M, et al. Adhesamine, a new synthetic molecule, accelerates differentiation and prolongs survival of primary cultured mouse hippocampal neurons. Biochem J. 2010 Mar 29;427 (2) :297-304.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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