Nicotinic acid mononucleotide

Nicotinic acid mononucleotide (NAMN) is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+. Nicotinate mononucleotide is a substrate for nicotinamide mononucleotide/Nicotinic acid mononucleotide adenylyltransferase[1][2].

Product Specifications

CAS Number

[321-02-8]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/nicotinic-acid-mononucleotide.html

Purity

99.76

Solubility

H2O : 10 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@H]([N+]2=CC=CC(C([O-])=O)=C2)O[C@H](COP(O)(O)=O)[C@H]1O

Molecular Formula

C11H14NO9P

Molecular Weight

335.20

References & Citations

[1]O'Hara JK, et al. Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum. PLoS One. 2014 Apr 18;9 (4) :e94061.|[2]Khan JA, et al. Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery. Expert Opin Ther Targets. 2007 May;11 (5) :695-705.