Afatinib

850140-72-6

(S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

BIBW 2992

0.9876

≥49.3 mg/mL in DMSO; ≥13.07 mg/mL in EtOH with ultrasonic; insoluble in H2O

CN(C)C/C=C/C(NC(C=C(C(NC1=CC(Cl)=C(F)C=C1)=NC=N2)C2=C3)=C3O[C@H]4CCOC4)=O

C24H25ClFN5O3

485.94

Blue ice

Store at -20°C.