Pravastatin (sodium)
Pravastatin sodium (CS-514 sodium) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.
Product Specifications
CAS Number
[81131-70-6]
Product Name Alternative
CS-514 (sodium)
UNSPSC
12352211
Hazard Statement
H302, H351, H361
Target
Autophagy; Ferroptosis; HMG-CoA Reductase (HMGCR)
Type
Natural Products
Related Pathways
Apoptosis; Autophagy; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/pravastatin-sodium.html
Purity
99.38
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL
Smiles
O[C@@H](C[C@@H](O)CC(O[Na])=O)CC[C@@H]([C@H](C=C1)C)[C@@](C1=C[C@@H](O)C2)([H])[C@H]2OC([C@@H](C)CC)=O
Molecular Formula
C23H35NaO7
Molecular Weight
446.51
Precautions
H302, H351, H361
References & Citations
[1]McTavish D, et al. Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs. 1991 Jul;42 (1) :65-89.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
Launched
Citation 01
Cell Syst. 2018 Apr 25;6 (4) :424-443.e7.|Chin J Integr Med. 2024 May 16.|FEBS Open Bio. 2025 Aug 8.|Front Cell Dev Biol. 2022 Mar 3;10:806081.|Research Square Preprint. 2022 Feb.|Biochem Pharmacol. 2025 Oct:240:117120.|Front Cell Dev Biol. 2020 May 28;8:404.
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2578059-01 24 Tests (Limit 1)
PGFM (13,14 dihydro 15 keto Prostaglandin F2 Alpha) ELISA Kit
Ask
View Details