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Pravastatin (sodium)

Pravastatin sodium (CS-514 sodium) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.

Product Specifications

CAS Number

81131-70-6

Product Name Alternative

CS-514 (sodium)

UNSPSC

12352211

Hazard Statement

H302, H351, H361

Target

Autophagy; Ferroptosis; HMG-CoA Reductase (HMGCR)

Type

Natural Products

Related Pathways

Apoptosis; Autophagy; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/pravastatin-sodium.html

Purity

99.38

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL

Smiles

O[C@@H](C[C@@H](O)CC(O[Na])=O)CC[C@@H]([C@H](C=C1)C)[C@@](C1=C[C@@H](O)C2)([H])[C@H]2OC([C@@H](C)CC)=O

Molecular Formula

C23H35NaO7

Molecular Weight

446.51

Precautions

H302, H351, H361

References & Citations

[1]McTavish D, et al. Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs. 1991 Jul;42 (1) :65-89.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Natural Products

Clinical Information

Launched

Citation 01

Cell Syst. 2018 Apr 25;6 (4) :424-443.e7.|Chin J Integr Med. 2024 May 16.|FEBS Open Bio. 2025 Aug 8.|Front Cell Dev Biol. 2022 Mar 3;10:806081.|Research Square Preprint. 2022 Feb.|Biochem Pharmacol. 2025 Oct:240:117120.|Front Cell Dev Biol. 2020 May 28;8:404.

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