6-Hydroxy-DOPA

6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer[1].

Product Specifications

CAS Number

[21373-30-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/6-hydroxy-dopa.html

Purity

98.37

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC(C(N)CC1=C(C=C(O)C(O)=C1)O)=O

Molecular Formula

C9H11NO5

Molecular Weight

213.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Chandramouly G, et al. Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers. Chem Biol. 2015;22 (11) :1491-1504.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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