6-Hydroxy-DOPA
6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer[1].
Product Specifications
CAS Number
21373-30-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-hydroxy-dopa.html
Purity
98.37
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC(C(N)CC1=C(C=C(O)C(O)=C1)O)=O
Molecular Formula
C9H11NO5
Molecular Weight
213.19
Precautions
H302, H315, H319, H335
References & Citations
[1]Chandramouly G, et al. Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers. Chem Biol. 2015;22 (11) :1491-1504.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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