Thio-TEPA
Product Specifications
UNSPSC Description
Thio-TEPA is a DNA alkylating agent, with antitumor activity.
Target Antigen
Antibiotic; Bacterial; DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Anti-infection;Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Thio-TEPA.html
Solubility
DMSO : ≥ 50 mg/mL|H2O : < 0.1 mg/mL (ultrasonic)
Smiles
S=P(N1CC1)(N2CC2)N3CC3
Molecular Weight
189.22
References & Citations
[1]Hagen B, et al. Metabolism and alkylating activity of thio-TEPA in rat liver slice incubation. Cancer Chemother Pharmacol. 1991;28(6):441-7.|[2]Down JD, et al. Thiotepa improves allogeneic bone marrow engraftment without enhancing stem cell depletion in irradiated mice. Bone Marrow Transplant. 1998 Feb;21(4):327-30.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-17574/Thio-TEPA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-17574/Thio-TEPA-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
52-24-4
Available Sizes
Curated Selection
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