Thio-TEPA
Thio-TEPA is a DNA alkylating agent, with antitumor activity.
Product Specifications
CAS Number
52-24-4
UNSPSC
12352005
Hazard Statement
H300, H350
Target
Antibiotic; Bacterial; DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Thio-TEPA.html
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
S=P(N1CC1)(N2CC2)N3CC3
Molecular Formula
C6H12N3PS
Molecular Weight
189.22
Precautions
H300, H350
References & Citations
[1]Hagen B, et al. Metabolism and alkylating activity of thio-TEPA in rat liver slice incubation. Cancer Chemother Pharmacol. 1991;28 (6) :441-7.|[2]Down JD, et al. Thiotepa improves allogeneic bone marrow engraftment without enhancing stem cell depletion in irradiated mice. Bone Marrow Transplant. 1998 Feb;21 (4) :327-30.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC230658L3V 200 µL
ZFAT (NM_001174158) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
AZA0A8M6Z0P5-Biotin 100 µg/Vial
Anti-Zebrafish HOOK3 Antibody Biotin Conjugated
Sign In for Pricing
View Details OR1042853-01 250 mg
1,2,3,4,5,6,7,8-octahydro-1-[ (4-methoxyphenyl) methyl]isoquinoline
Sign In for Pricing
View Details OR1042853-02 1 g
1,2,3,4,5,6,7,8-octahydro-1-[ (4-methoxyphenyl) methyl]isoquinoline
Sign In for Pricing
View Details OR1042853-03 5 g
1,2,3,4,5,6,7,8-octahydro-1-[ (4-methoxyphenyl) methyl]isoquinoline
Sign In for Pricing
View Details