MMV024101
MMV024101 shows potency against P. falciparum NF54 with an IC50 value of 543 nM, which has antiplasmodial activity[1].
Product Specifications
CAS Number
[1092565-44-0]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mmv024101.html
Smiles
O=S(N)(C1=CC(C2=NC3=C(C=C2)N=CC=C3C4=CNN=C4)=CN=C1)=O
Molecular Formula
C16H12N6O2S
Molecular Weight
352.37
References & Citations
[1]Kandepedu N, et al. Identification, Characterization, and Optimization of 2,8-Disubstituted-1,5-naphthyridines as Novel Plasmodium falciparum Phosphatidylinositol-4-kinase Inhibitors with in Vivo Efficacy in a Humanized Mouse Model of Malaria. J Med Chem. 2018 Jul 12;61 (13) :5692-5703.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112728/MMV024101-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112728/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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