MMV024101

MMV024101 shows potency against P. falciparum NF54 with an IC50 value of 543 nM, which has antiplasmodial activity[1].

Product Specifications

CAS Number

[1092565-44-0]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mmv024101.html

Smiles

O=S(N)(C1=CC(C2=NC3=C(C=C2)N=CC=C3C4=CNN=C4)=CN=C1)=O

Molecular Formula

C16H12N6O2S

Molecular Weight

352.37

References & Citations

[1]Kandepedu N, et al. Identification, Characterization, and Optimization of 2,8-Disubstituted-1,5-naphthyridines as Novel Plasmodium falciparum Phosphatidylinositol-4-kinase Inhibitors with in Vivo Efficacy in a Humanized Mouse Model of Malaria. J Med Chem. 2018 Jul 12;61 (13) :5692-5703.