DSPE-PEG2000-triGalNAc (ammonium)
DSPE-PEG2K-triGalNAc is a polar lipid composed of DSPE and tri-N-acetylgalactosamine that can be used to construct liposomes target to asialoglycoprotein receptor (ASGPR) .
Product Specifications
CAS Number
[2936651-86-2]
UNSPSC
12352211
Target
Liposome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dspe-peg2000-trigalnac-ammonium.html
Purity
99.8
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCCCCCC(O[C@]([H])(COC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(COCCOCC(NCCCCC(N(CC(NCCOCCOCCO[C@H]1O[C@H]([C@H]([C@H]([C@@H]1NC(C)=O)O)O)CO)=O)CC(NCCOCCOCCO[C@H]2O[C@H]([C@H]([C@H]([C@@H]2NC(C)=O)O)O)CO)=O)C(NCCOCCOCCO[C@H]3O[C@H]([C@H]([C@H]([C@@H]3NC(C)=O)O)O)CO)=O)=O)=O)([O-])=O)=O.[NH4+].[n]
Molecular Formula
(C2H4O) nC97H180N9O38P.H3N
Molecular Weight
2000 (Average)
References & Citations
[1]Green Ahn, et al. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation. Nat Chem Biol. 2021, 17, 9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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